منابع مشابه
Cloning of the kanamycin resistance gene from a kanamycin-producing Streptomyces species.
A kanamycin-producing strain, Streptomyces kanamyceticus ISP5500, is resistant to kanamycin. A kanamycin resistance determinant was cloned from S. kanamyceticus into Streptomyces lividans 1326, using the plasmid vector pIJ702. The resulting plasmid, pMCP5, could also transform Streptomyces lavendulae S985 and Streptomyces parvulus 2283 to kanamycin resistance. Transformants carrying pMCP5 were ...
متن کاملModulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering
Both kanamycin A and kanamycin B, antibiotic components produced by Streptomyces kanamyceticus, have medical value. Two different pathways for kanamycin biosynthesis have been reported by two research groups. In this study, to obtain an optimal kanamycin A-producing strain and a kanamycin B-high-yield strain, we first examined the native kanamycin biosynthetic pathway in vivo. Based on the prop...
متن کاملKanamycin in the treatment of rectal gonorrhoea.
The rate of treatment failure in cases of rectal gonorrhoea has been the source of considerable concern in recent years and it was therefore decided to investigate the value of kanamycin for this condition. As pointed out by Jefferiss (1966), the true incidence of gonorrhoea in passive homosexuals is undoubtedly greater than the figures of proven infections would suggest, as there are many case...
متن کاملVentilatory effects of aerosolized kanamycin and polymyxin.
Inhalation of nebulized antibiotics is associated with respiratory distress in some patients but the effect on the airways has not been studied. Ventilatory function was studied immediately before and 20 minutes after inhalation in patients having chronic lung disease, who were being treated with inhaled antibiotics. Kanamycin was associated with minor changes in ventilatory function but polymy...
متن کاملPharmacokinetics of gentamicin and kanamycin during hemodialysis.
The pharmacokinetics of gentamicin, kanamycin, and creatinine were studied in patients undergoing hemodialysis. After intravenous injection of single doses of the drugs, 50 to 60% of the doses of both antibiotics were cleared from the body during a 6-h period; this occurred almost entirely by the hemodialysis process. No correlation was found between the dialysance of the aminoglycosides and cr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1962
ISSN: 0003-4932
DOI: 10.1097/00000658-196204000-00008